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Doctoral Thesis
DOI
https://doi.org/10.11606/T.5.2006.tde-12042006-135835
Document
Author
Full name
Ernesto Reggio
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2005
Supervisor
Committee
Pompeo, Antonio Carlos Lima (President)
Antonopoulos, Ioannis Michel
Figueiredo, José Alaor de
Hering, Flávio Luiz Ortiz
Rocha, Luis Carlos de Almeida
Title in Portuguese
"Tratamento percutâneo do adenocarcinoma de próstata por crioablação"
Keywords in Portuguese
Adenocarcinoma
Criocirurgia/métodos
Próstata
Abstract in Portuguese
Diversas são as formas de tratamento do câncer de próstata, com resultados oncológicos e complicações variadas . A crioablação foi proposta nos anos 60 e com a evolução dos métodos de imagem a técnica ressurgiu; 44 pacientes, divididos em 3 grupos (portadores de tumor de alto risco, tumores de baixo risco e falha de tratamento após radioterapia) foram submetidos a crioterapia por via percutânea transperineal. Sobrevida livre de doença foi de 87% no grupo baixo risco, 34% no grupo alto risco e 58% no grupo de resgate após falha de radioterapia. A complicação mais freqüente foi disfunção erétil (94,5%); obstrução infravesical ocorreu em 9 pacientes (20,4%); 6 pacientes (13,6%) apresentaram algum grau de incontinência urinária. Não houve nenhum caso de fístula uretroretal ou mortalidade relacionada ao procedimento
Title in English
Percutaneous treatment of prostate adenocarcinoma by cryoablation
Keywords in English
Adenocarcinoma
Cryosurgery/methods
Prostate
Abstract in English
There are several treatments for prostate cancer with an assorted oncologic results and complications. Cryoablation was proposed in the 60 and the improvement of radiological techniques allowed the perineal percutaneous treatment; 44 patients divided into three groups (high risk tumors, low risk tumors and patients with recurrent prostate cancer following radiotherapy) were submitted to perineal percutaneous prostate cryoablation. Biochemical-free survival was 87% in low risk group, 34% in the high-risk group and 58% in salvage cryoablation. Erectile dysfunction was the most frequent complication (94,5%); Infravesical obstruction occurred in 20,4% of the patients and six (13,6%) developed urinary incontinence. There were no urethrorectal fistulae or mortality related to the procedure
 
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Publishing Date
2006-05-16
 
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