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Master's Dissertation
DOI
10.11606/D.3.2012.tde-19072013-111032
Document
Author
Full name
Cristiane Mileo Batistela
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2012
Supervisor
Committee
Piqueira, José Roberto Castilho (President)
Caldas, Ibere Luiz
Kassab Junior, Fuad
Title in Portuguese
Medida de complexidade no fenômeno de ondas de depressão alastrante.
Keywords in Portuguese
Complexidade
Depressão alastrante
Desordem
Ordem
Abstract in Portuguese
O que se desejou apresentar neste trabalho é se a aplicação da medida de complexidade LMC no estudo do fenômeno da depressão alastrante mostra-se eficiente na perspectiva de contribuir para uma melhor compreensão do fenômeno. Para isso, usou-se como modelo experimental a retina de pintinho in vitro. Na tentativa de obter informações sobre estados de equilíbrio entre a ordem e desordem, propõe-se as análises dos registros de dois dos concomitantes do fenômeno: a alteração lenta do potencial extracelular e do sinal intrínseco óptico. Para isso, avaliou-se o efeito de manipulações fármaco-química sobre esses dois concomitantes do fenômeno e através de análises comparativas entre as ondas de controle e as ondas obtidas em presença das diversas substâncias foram discutidas a aplicabilidade do método proposto, mostrando que a medida de complexidade trouxe novas informações sobre a depressão alastrante contribuindo para um entendimento melhor do fenômeno.
Title in English
Measure of complexity in the phenomenon of spreading depression waves.
Keywords in English
Complexity
Disorder
Order
Spreading depression
Abstract in English
What we wanted to present in this work is the application of the LMC measure of complexity in the study of the phenomenon of spreading depression proves efficient in order to contribute to a better understanding of the phenomenon. For this, we used as an experimental model of the chick retina in vitro. In an attempt to obtain information about equilibrium states between order and disorder, it is proposed that the analysis of the records of two of the concomitant phenomena: a slowly changing the extracellular potential and intrinsic optical signal. For this, we evaluated the effect of pharmaco-chemical manipulations on these two concomitant phenomenon and by comparative analyzes of the control waves and the waves obtained in the presence of various substances discussed the applicability of the proposed method, the measure complexity brought new information on the spreading depression to a better understanding of the phenomenon.
 
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Publishing Date
2013-07-22
 
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