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Doctoral Thesis
DOI
10.11606/T.5.2004.tde-04102005-113802
Document
Author
Full name
Henrique Antonio Berwanger de Amorim Cabrita
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2004
Supervisor
Committee
Camargo, Olavo Pires de (President)
Aristide, Rudelli Sergio Andrea
Croci, Alberto Tesconi
Drumond, Sérgio Nogueira
Lima, Ana Lucia Lei Munhoz
Title in Portuguese
"Estudo comparativo do tratamento das artroplastias infectadas do quadril sem e com o uso do espaçador de cimento com antibiótico"
Keywords in Portuguese
ARTROPLASTIA DE QUADRIL/métodos
CIMENTO PARA OSSOS/uso terapêutico
ESTUDO COMPARATIVO
ESTUDOS PROSPECTIVOS
GRUPOS CONTROLE
INFECÇÕES RELACIONADAS À PRÓTESE/cirurgia
INFECÇÕES RELACIONADAS À PROTESE/complicações
VANCOMICINA/uso terapêutico
Abstract in Portuguese
Em um estudo prospectivo sobre o tratamento das artroplastias de quadril infectadas, com perdas ósseas e fístulas ativas, 25 pacientes foram tratados em dois tempos e 36 pacientes foram tratados em dois tempos com espaçador de cimento impregnado com vancomicina. O acompanhamento médio foi de dois anos e onze meses. A taxa de recidiva infecciosa foi de 29,2% nos tratados em dois tempos e de 8,8% nos tratados com espaçador. O Escore de Harris para Quadril médio passou de 19,3 para 69,0 pontos nos casos tratados em dois tempos e de 19,7 para 72,2 pontos nos pacientes tratados com espaçador. Ao final do estudo, 86,1% dos tratados com espaçador e em 33,3% dos tratados em dois tempos tinham próteses em bom funcionamento e sem infecção. O espaçador de cimento com antibiótico é o tratamento de escolha nas próteses infectadas de quadril
Title in English
Prospective study of the treatment of chronically infected hip replacements with and without the use of an antibiotic-loaded acrylic cement spacer
Keywords in English
ARTHROPLASTY REPLACEMENT HIP/methods
BONE CEMENTS/therapeutic use
COMPARATIVE STUDY
CONTROL GROUPS
PROSPECTIVE STUDIES
PROSTHESIS-RELATED INFECTIONS/complications
PROSTHESIS-RELATED INFECTIONS/surgery
VANCOMYCIN/therapeutic use
Abstract in English
We report a prospective study of 61 patients with chronically deep infected hip replacements with actively discharging sinuses, treated with a two-stage revision protocol, with and without a cement spacer impregnated with vancomycin. The average follow-up was two years and eleven months. Twenty-five patients were treated without a spacer and seven had recurrence of infection. Thirty-three patients were treated with a spacer and three had recurrence of infection. The average Harris Hip score increased from 19,3 to 69,0 on the non-spacer patients and from 19,7 to 75,2 on the spacer group. At the end of the study, the success rate was 86,1% for the spacer group and 33,3% for the non-spacer group. The use of the spacer increased the results of the two-stage chronic infected hip replacements
 
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Publishing Date
2005-10-05
 
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