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Doctoral Thesis
DOI
10.11606/T.5.2005.tde-02092005-111313
Document
Author
Full name
Maria Cristina Guerra Passarelli
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2005
Supervisor
Committee
Jacob Filho, Wilson (President)
Bérgamo, Ronaldo Roberto
Giglio, Auro Del
Natale, Valeria Maria
Rozenfeld, Suely
Title in Portuguese
"Reações adversas a medicamentos em uma população idosa hospitalizada"
Keywords in Portuguese
FATORES DE RISCO
HOSPITALIZAÇÃO
IDOSO
REVISÃO DE USO DE MEDICAMENTOS
SISTEMAS DE NOTIFICAÇÃO DE REAÇÕES ADVERSAS A MEDICAMENTOS
Abstract in Portuguese
Nesta pesquisa foram avaliados 186 idosos hospitalizados quanto ao aparecimento de reações adversas a medicamentos (RAM). Encontrou-se 199 RAM (1,07 por paciente). Para 11,3% dos idosos a RAM constituiu a causa da internação, para 17,2% estava presente à internação mas não como causa e 46,2% apresentaram RAM durante a hospitalização. As RAM sérias mais comuns foram a insuficiência renal aguda, a hipercalemia e a hipotensão postural. Concluiu-se que houve uma prevalência importante de RAM nesses pacientes, encontrando-se como fatores de risco significativos o número de diagnósticos, o número de medicamentos e o uso de medicamento inapropriado para idosos
Title in English
Adverse drug reactions among an elderly hospitalized population
Keywords in English
ADVERSE DRUG REACTION REPORTING SYSTEMS
AGED
DRUG UTILIZATION REVIEW
HOSPITALIZATION
RISK FACTORS
Abstract in English
The present study evaluated the prevalence of adverse drug reactions (ADR) among 186 hospitalized elderly. A total of 199 ADR were founded (1.07 per patient). For 11.3% of the patients the ADR was the cause of hospitalization, for 17.2% the ADR was present at hospitalization but not as the cause and for 46.2% it was presented during hospitalization. The most common serious ADR were acute renal insufficiency, hyperkalemia and postural hypotension. We concluded that a significant prevalence of ADR was found among that patients, with the number of diagnosis, the number of drugs and the use of a drug considered to be inappropriate as risk factors
 
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Publishing Date
2005-10-07
 
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