• JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
 
  Bookmark and Share
 
 
Doctoral Thesis
DOI
10.11606/T.5.2005.tde-15082005-120445
Document
Author
Full name
Mauro Canzian
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2005
Supervisor
Committee
Capelozzi, Vera Luiza (President)
Altemani, Albina Messias de Almeida Milani
Antonangelo, Leila
Deheinzelin, Daniel
Jatene, Fabio Biscegli
Title in Portuguese
"Análise qualitativa e semiquantitativa de parâmetros morfológicos em biópsias pulmonares cirúrgicas e autópsias: valor preditivo e impacto no prognóstico de pacientes com infiltrado pulmonar difuso"
Keywords in Portuguese
AUTÓPSIA
BIÓPSIA/métodos
INSUFICIÊNCIA RESPIRATÓRIA/patologia
PROGNÓSTICO
PULMÃO/patologia
VALOR PREDITIVO
Abstract in Portuguese
Dados clínicos e histológicos referentes a biópsias pulmonares cirúrgicas de 63 pacientes adultos, com infiltrado difuso, a maior parte em insuficiência respiratória, foram analisados. A severidade de cada alteração histopatológica foi avaliada semiquantiativamente segundo um sistema histológico de escores. "Índices" agudo e crônico foram estabelecidos. Associação estatiscamente significante ocorreu entre a sobrevida e idade, dano alveolar difuso, comorbidade e "índice crônico". A análise histológica detalhada de espécimes pulmonares mostrou-se mais informativa do que o simples diagnóstico nosológico. Maiores estudos prospectivos com adequada casualização poderão confirmar esta conclusão
Title in English
Qualitative and semiquantitative analyses of morphological parameters of open lung biopsies and autopsies : predictive value and impact on prognosis of patients with diffuse pulmonary infiltrate
Keywords in English
AUTOPSY
BIOPSY/methods
LUNG/pathology
PREDICTIVE VALUE
PROGNOSIS
RESPIRATORY INSUFFICIENCY/pathology
Abstract in English
Clinical and histological data concerning open lung biopsy from 63 adult patients, with diffuse infiltrates, most of them with respiratory failure, from 1982 to 2003, were analyzed. Severity of each pathological alteration was semiquantitatively rated following an histological score system. "Acute" and "chronic" indices were then established. Statistically significant association occurred between survival and increasing age, diffuse alveolar damage, comorbidity and the "chronic score". Detailed histological analysis of lung specimens was proven to provide more than nosological diagnosis. Greater studies in a randomized and prospective trial could finalize and confirm this conclusion
 
WARNING - Viewing this document is conditioned on your acceptance of the following terms of use:
This document is only for private use for research and teaching activities. Reproduction for commercial use is forbidden. This rights cover the whole data about this document as well as its contents. Any uses or copies of this document in whole or in part must include the author's name.
MauroCanzian.pdf (905.92 Kbytes)
Publishing Date
2005-08-15
 
WARNING: Learn what derived works are clicking here.
All rights of the thesis/dissertation are from the authors
Centro de Informática de São Carlos
Digital Library of Theses and Dissertations of USP. Copyright © 2001-2020. All rights reserved.