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Doctoral Thesis
DOI
10.11606/T.5.2005.tde-05102005-114154
Document
Author
Full name
Claudio Luders
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2005
Supervisor
Committee
Romão Junior, João Egidio (President)
Abensur, Hugo
Figueiredo, Carlos Eduardo Poli de
Gordan, Pedro Alejandro
Ianhez, Luiz Estevam
Title in Portuguese
"Avaliação do transporte e cinética de solutos em pacientes submetidos à hemodiálise diária de alto fluxo, alta eficiência e curta duração"
Keywords in Portuguese
DIÁLISE RENAL/métodos
FATORES DE TEMPO
INSUFICIÊNCIA RENAL CRÔNICA/terapia
Abstract in Portuguese
Nos últimos anos, em função dos resultados negativos do HEMO Study e da elevada mortalidade na população dialítica, observou-se crescente interesse nosregimes de hemodiálise diária. A dose de diálise persiste como um dos elementos fundamentais na adequação do tratamento dialítico. Comparamos as doses de diálise em hemodiálise diária (90 minutos, 6 vezes / semana), com as doses em hemodiálise convencional (240 minutos, 3 vezes / semana), através da quantificação direta da diálise, do modelo de cinética de uréia e pelo Standard Kt/V de Gotch. A comparação foi feita para diferentes solutos (uréia, creatinina, fósforo, ácido úrico e ß2-microglobulina) e diferentes taxas de ultrafiltração
Title in English
Solutes transport and kinetics assessment in patientes submitted to a high flux, high efficiency and short length daily hemodialysis
Keywords in English
KIDNEY FAILURE CHRONIC/therapy
RENAL DIALYSIS/methods
TIME FACTORS
Abstract in English
The recent efforts to improve dialysis outcome and the negative results from the HEMO Study have created great interest on alternative hemodialysis (HD) regimens. Dialysis dose persist fundamental to HD adequacy. However, parameters of adequacy have not been validated to Daily HD. We compared the dialysis dose of daily, high efficiency and flux HD (90 minutes, 6 times a week) with Conventional high flux HD (240 minutes, 3 times a week) by direct dialysis quantification, urea kinetics model and Gotch's stdKt/V. The comparison was made with urea, creatinine, phosphate, uric acid and ß2-microglobulin. We, also, analyzed the effect of different ultrafiltration rates on solute removal on Daily HD
 
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ClaudioLuders.pdf (662.24 Kbytes)
Publishing Date
2005-10-05
 
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