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Doctoral Thesis
DOI
10.11606/T.5.2006.tde-16052006-133605
Document
Author
Full name
Fernando Bliacheriene
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2005
Supervisor
Committee
Auler Junior, Jose Otavio Costa (President)
Carmona, Maria Jose Carvalho
Cruz Junior, Ruy Jorge
Ferez, David
Torres, Marcelo Luis Abramides
Title in Portuguese
"Estudo da variação da pressão sistólica e suas componentes como preditoras de hipovolemia em coelhos submetidos à hemorragia e pneumoperitônio"
Keywords in Portuguese
Coelhos
Hemorragia
Hipovolemia
Laparoscopia
Monitorização fisiológica
Pneumoperitônio
Pressão arterial
Abstract in Portuguese
Objetivos A variação da pressão sistólica (VPS) é parâmetro de avaliação hemodinâmica em indivíduos ventilados mecanicamente. O objetivo deste estudo foi investigá-la em coelhos submetidos à hemorragia e pneumoperitônio. Método Estudou-se 11 coelhas sob 4 tratamentos: após 20 minutos de estabilização (T1); pneumoperitônio de 10mmHg por 30 minutos (T2); hemorragia de 20% da volemia estimada, realizada em 10 minutos, mais 10 minutos de estabilização, na vigência de pneumoperitônio (T3); após reposição do sangue retirado, em 10 minutos, mais 10 minutos de estabilização, sem pneumoperitônio (T4). Resultados Observou-se aumento de VPS significativo (p < 0,05) em T2 e T3, com maior valor em T3, em relação a T1 e que não houve diferença significativa entre T4 e T1. Delta Down tem maior participação na VPS nos tratamentos T1, T3 e T4. Em T2 a contribuição de ambas é equilibrada. Conclusões VPS mostrou ser preditora de hipovolemia durante hemorragia e pneumoperitônio
Title in English
Study on systolic pressure variation and its components as predictors of hypovolemia in rabbits submitted to hemorrhage and pneumoperitoneum
Keywords in English
Blood pressure
Hemorrhage
Hypovolemia
Laparoscopy
Monitoring physiologic
Pneumoperitoneum
Rabbits
Abstract in English
Systolic pressure variation (SPV) is a hemodynamic analysis parameter for mechanically ventilated individuals. The aim of this study was to investigate it in rabbits submitted to hemorrhage and pneumoperitoneum. Methods Eleven rabbits were studied under 4 treatments: after 20 minutes of stabilization (T1); 10 mmHg pneumoperitoneum for 30 minutes (T2); hemorrhage of 20% of the estimated volemia, performed in 10 minutes, followed by 10 minutes of stabilization, under pneumoperitoneum (T3); re-infusion in 10 minutes of the blood shed and more 10 minutes of stabilization, without pneumoperitoneum (T4). Results There was a significant increase in SPV (p < 0.05) in T2 and T3, with a higher value in T3, related to T1 and no difference between T4 and T1. Delta Down is the main component in T1, T3 and T4, while in T2 it is balanced with Delta Up. Conclusions SPV showed to be predictor of hypovolemia during hemorrhage and pneumoperitoneum
 
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Publishing Date
2006-05-19
 
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