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Doctoral Thesis
DOI
10.11606/T.5.2009.tde-10092009-094255
Document
Author
Full name
Natália Cristina de Oliveira Vargas e Silva
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2009
Supervisor
Committee
Bonfa, Eloisa Silva Dutra de Oliveira (President)
Borba Neto, Eduardo Ferreira
Kiss, Maria Augusta Peduti Dal Molin
Teixeira, Luzimar Raimundo
Zerbini, Cristiano Augusto de Freitas
Title in Portuguese
Estudo da segurança e eficácia do exercício aeróbico em pacientes com esclerose sistêmica
Keywords in Portuguese
Escleroderma sistêmico
Exercício
Lactato sanguíneo
Saturação de oxigênio
Teste de esforço
Abstract in Portuguese
OBJETIVO: Diversos estudos demonstraram que pacientes com Esclerose Sistêmica possuem capacidade aeróbia reduzida. É relevante avaliar se o exercício aeróbio é seguro e eficaz para estes pacientes. MÉTODO: Sete pacientes com Esclerose Sistêmica e sete controles saudáveis participaram de um programa de oito semanas, que consistiu em atividade aeróbia de intensidade moderada duas vezes por semana. RESULTADOS: Pacientes e controles apresentaram aumento significativo no pico de consumo de oxigênio, e foram capazes de executar uma intensidade de exercício significativamente maior em relação ao pré-teste. O grupo Esclerose Sistêmica demonstrou aumento na saturação de oxigênio no pico do exercício. O escore de Rodnan foi similar antes e após a intervenção, e as úlceras digitais e o fenômeno de Raynaud permaneceram estáveis. CONCLUSÃO: O exercício aeróbio foi seguro e eficaz para pacientes com Esclerose Sistêmica, portanto, aumentar a capacidade aeróbia é uma meta possível no tratamento desta doença.
Title in English
Study of safety and efficacy of aerobic exercise in systemic sclerosis patients
Keywords in English
Blood lactate
Ergospirometry
Exercise
Oxygen saturation
Systemic sclerosis
Abstract in English
OBJECTIVES: Several studies have established that Systemic Sclerosis patients have a reduced exercise capacity. It is relevant to evaluate whether aerobic exercise consists in a safe and effective intervention for these patients. METHODS: Seven Systemic Sclerosis patients and seven healthy sedentary controls were enrolled in an eight-week program consisting of moderate intensity aerobic exercise twice a week. RESULTS: Systemic Sclerosis patients and controls had a significant improvement in their peak oxygen consumption and were able to perform a significantly higher exercise intensity when compared to baseline. Systemic sclerosis group improved peak exercise oxygen saturation. Rodnan score was similar before and after the intervention. Digital ulcers and Raynauds phenomenon remained stable. CONCLUSIONS: Aerobic exercise was safe and effective in patients with Systemic Sclerosis, therefore increasing aerobic capacity is a feasible goal in the management of this disease.
 
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nataliacovesilva.pdf (552.87 Kbytes)
Publishing Date
2009-09-11
 
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